Patient Guide: Liposuction for LymphedemaBy: Lindsay Davey, MScPT, MSc, CDT
April 3, 2018
Editors: Ryan Davey, PhD and Lindsay Davey, MScPT, MSc, CDT
A specialized form of liposuction for lymphedema has been successfully used to treat advanced cases of lymphedema for decades. Despite this success, it remains a poorly understood and uncommon surgical treatment for advanced lymphedema.
Lymphedema is a chronic swelling condition characterized by an excessive accumulation of lymph fluid, most often in an arm or leg. Predictably, the treatment of lymphedema focuses on strategies to remove this excess fluid, and prevent further accumulation – such as via compression garments and manual lymphatic drainage massage. Under this paradigm, using liposuction for lymphedema doesn’t appear, on the surface, to make a lot of sense – since it targets fat rather than fluid. In fact, liposuction is generally considered to be both risky and counter-productive in this population; people with lymphedema are discouraged from even getting blood drawn from their afflicted limb for risk of sparking inflammation or infection. But for a subset of lymphedema patients, liposuction can profoundly improve their lives.
Liposuction for lymphedema: Is it effective? Is it safe?
Which patients might be helped by liposuction?
Liposuction (or “suction-assisted lipectomy”) is a very common cosmetic surgery used to remove fat, not fluid. For cases of lymphedema that are classified as stage 1 – where swelling is predominately comprised of excess lymph fluid, liposuction would not only be ineffective, this invasive procedure would further damage lymphatic and blood vessels, promote inflammation, risk infection, and generally exacerbate symptoms.
However, in cases of lymphedema that have progressed to stage 2, we see things begin to change. Swelling gradually becomes more firm, dense, unaffected by elevation, and “non-pitting” – meaning that if you press your thumb into the swelling it will not leave a temporary indent. The pitting test can be used as an indicator that the swelling is no longer primarily lymph fluid, but has instead morphed into significant amounts of fat (adipose tissue) and fibrous scar tissue – physiological changes that occur as a byproduct of prolonged lymph fluid accumulation. (You can learn more about the connection between lymph fluid and adipose here: Untreated Lymphatic Swelling Promotes Weight Gain by Altering Stem Cell Behaviour).
By the third stage of lymphedema the swelling has progressed even further, becoming very firm, irreversible, and usually physically debilitating. It is at this stage that the excess limb volume is primarily comprised of adipose tissue (along with a corresponding increase in muscle and bone mass – an adaptive response to the extra mechanical load imposed by the excess fat), rather than fluid (ref 1).
For patients who have progressed to stage 3, standard lymphedema treatment practices are no longer able to significantly decrease limb size – but liposuction can. The benefits of compression and manual lymphatic drainage at this stage is primarily limited to removing small amounts of fluid and preventing further swelling. Even if an experimental surgical procedure could repair the underlying lymphatic dysfunction in these patients, they would experience little or no reduction in limb size. It is for this subset of patients with stage 3 disease, that lymphedema liposuction has been shown to be very effective at safely reducing the excess fat – and often with dramatic results.
Liposuction for lymphedema is still a relatively uncommon procedure, but the results can be striking. Pioneered by Dr Hakan Brorson (Skane University Hospital, Malmo, Sweden) over 20 years ago, this specialized procedure has been slow to be adopted into clinical practice around the world, despite promising results for both arm and leg lymphedema. For patients whose excess volume is due to adipose tissue, liposuction combined with compression has been shown to remove up to 100% of the excess volume (ref 2) – up to 4L of aspirate in the case of arm lymphedema – and without further impairing lymphatic function (ref 3). Maximum limb size reduction is typically observed by 6 months (ref 4), and with proper on-going post-surgical lymphedema management, recurrence in the long-term appears to be avoidable (ref 4, 5). The best outcomes are seen for patients who are regularly monitored, and who follow best lymphedema management practices including ongoing compression. The pictures below show an example of Dr. Brorson’s work on a patient with stage 3 lymphedema of the right leg. This patient had a very positive outcome from the lymphedema liposuction procedure they received.
What about for Head and Neck Lymphedema? There have only been a small handful of studies to investigate liposuction for this patient population, and our take is that the jury is still out with respect to how it should be performed, who should receive it, and how effective it might be (see: Liposuction for Head and Neck Lymphedema – Does it Work? For Which Patients?). Our baseline assumption is that if it is delivered in a manner similar to liposuction for arm and leg lymphedema, and on patients with similar characteristics, it should be similarly effective.
Is liposuction for lymphedema a cosmetic procedure?
Yes and no. It could certainly improve the aesthetics of the limb and associated patient self-image. But it can also help reduce physical impairment, improve patient quality of life, and potentially even partially improve lymphatic function in the limb (more on this below).
Is liposuction a cure for advanced stage lymphedema?
No. Patients that undergo liposuction for lymphedma still have an underlying lymphatic dysfunction, and so they will still need to manage their condition to prevent swelling and disease progression that got them to stage 3 lymphedema in the first place. That said, when liposuction is performed successfully it can break the vicious cycle of disease progression and offer some patients a life-changing fresh start – the ultimate ‘do-over’.
Are you a good candidate for lymphedema liposuction?
Liposuction surgery for lymphedema has risks associated with it, significant cost, and significant effort. Its effectiveness and the ultimate satisfaction of the patient will depend on the suitableness of the patient and the skill of the surgical and lymphatic pre- and post-operative team.
The below indications and contraindications can help you determine if you are a good candidate, but discussing with your family doctor and lymphedema therapist is necessary to make the best decision for you (as well as to effectively prepare yourself as a candidate).
Indications for treating lymphedema with liposuction
- You have a diagnosis of advanced primary or secondary lymphedema
- AND swelling is comprised of excess adipose tissue NOT lymph fluid:
- Excess arm or leg volume with no ‘pitting’. Pitting is an indication of excess lymph fluid rather than adipose tissue. Pitting can be evaluated by pressing the thumb very hard into the swelling (as hard as possible) for one minute. If the swelling is due to fluid rather than primarily adipose tissue, this procedure should leave a temporary thumb print, as seen in early stages of lymphedema. The pioneering Swedish group led by Dr. Brorson now accepts patients with very minimal pitting if maximal treatment is unable to further reduce the swelling to a completely non-pitting state (no more than 4-5mm of pitting depth in arm and 6-7 mm in leg).
- Swelling does not respond to conservative treatment despite maximal effort by a lymphedema therapist trained in combined decongestive therapy (CDT). Once all lymph related swelling is removed from the arm, and no pitting is present, any remaining excess volume can likely be attributed to excess adipose tissue.
- AND you have considerable functional impairment and/or cosmetic deformity or other complications such as inflammatory attacks or repeat infection (AFTER having excess lymph-fluid removed by combined decongestive therapy).
- AND You have none of the contraindications below.
Contraindications for treating lymphedema with liposuction
The following conditions would exclude patients from being good candidates for liposuction (ref 4):
- Patient has NOT undergone maximum conservative treatment pre-operatively.
- Patient shows ‘pitting’ – which indicates the presence of excess lymph fluid.
- Metastatic cancer
- Open wounds
- Blood coagulation disorders
- Not healthy enough to undergo surgery
- Patient does not agree to faithfully wear compression garments and follow other best management practices after surgery. Not only is liposuction not a cure for lymphedema, the procedure itself could worsen symptoms if appropriate post-operative care is not taken. In fact, compression and manual lymphatic drainage massage is frequently used after purely cosmetic liposuction as part of the recovery process – to help reduce the swelling and fibrosis liposuction can cause in otherwise normal individuals.
In addition to the above, Dr Brorson recommends that patients who smoke cigarettes to stop doing so at least one month prior to the surgery. This will ensure maximal blood supply to the skin (smoking constricts small blood vessels), which can help increase the likelihood of a good outcome.
Liposuction Clinical Decision Tree: Am I a Good Candidate?
The flow chart below outlines the major clinical decisions that can be used to help determine patient candidacy for lymphedema liposuction.
What does lymphedema liposuction entail?
Liposuction for lymphedema entails significant cost, risk, and commitment – commitment to finding the right team, undergoing the procedure, and following appropriate life-long best management practices thereafter. This form of minimally invasive liposuction is sometimes called “suction-assisted protein lipectomy”, and it should only be performed by surgeons trained to treat lymphedema, and delivered within a comprehensive lymphedema management program.
Here’s what the general procedure looks like:
- Liposuction is performed under general anesthetic. Blood is kept out of the limb by use of a tourniquet. The surgeon makes a series of incisions around the circumference of the limb, through which a specialized suction tube (a ‘cannula’) is inserted. These incisions are small and do not require stiches. Suctioning out fat begins at one end of the limb and progresses to the other end, removing as much fat as possible along the way. No liposuction is performed in the hand or foot as these areas do not accumulate lymphedema-related adipose tissue. The overall procedure usually takes a couple of hours, but will require a hospital stay for up to a week.
- As an essential part of post-operative care, a custom fit compression garment is applied in the operating room to reduce bleeding and post-operative swelling. Hand and foot compression is also applied.
- Following the procedure, garments are worn continuously 24 hours per day, removing only for bathing and changing the compression garment. (Having more than one garment is important not just to maintain good arm/leg hygiene, but also the act of washing and drying the compression garment will help ‘reactivate’ its compressive properties). Skin should also be moisturized after bathing to prevent drying and decrease risk of infection. Garments are reduced in size or replaced as the swelling subsides to ensure continued effective compression.
- Even after the maximum amount of swelling reduction has been achieved, patients are recommended to wear their garments as continuously as possible. According to Dr. Brorson, it may take up to 2-3 years before the new arm volume becomes stable, after which reliance on compression garments may potentially be reduced.
What outcomes might you expect?
When liposuction is performed on a suitable candidate by a qualified surgeon trained in liposuction for lymphedema, and in concert with coordinated pre- and post- management by a lymphatic therapist the procedure should not further impair lymphatic function, and the following outcomes have be observed:
- Significant reduction in adipose tissue with corresponding functional and cosmetic improvements and associated improvement in patient quality of life (increased mobility, more positive self-image, decreased pain)
- Decreased incidence of cellulitis (infection) by as much 75 – 87%, likely in part due to improved blood flow in the skin (ref 5,6).
- Possibility of a small improvement in lymphatic function as a result of better blood flow, less lymph production (due to less adipose tissue), and less physical compression of lymphatic vessels within the limb, which allows for better lymph flow. However, the patient’s underlying lymphatic impairment remains and so preventing recurrence of lymphedema accumulation requires life-long management.
- Prevention of reoccurrence of disease progression with appropriate life-long post-surgical management.
- Skin numbness (usually short term)
- Pain (usually short term)
- Skin irritation caused by the compression garment
Where can you have this liposuction procedure performed?
This is the tricky part. I’m sorry to say that it is unlikely that you have a local surgeon who is trained to perform this procedure. I know of one local Toronto surgeon who has expressed to me his interest in being trained, but currently I am not aware of anyone in Canada who performs this procedure. Below I have compiled an incomplete list of teams that offer liposuction for lymphedema around the world:
- The pioneer of this procedure is Dr. Hakan Brorson of Sweden. His minimally invasive surgical approach is delivered within a broader program of lymphedema management, and is supported by a variety of peer-reviewed clinical studies. He has trained teams around the world:
- Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
- Stanford University School of Medicine, Palo Alto, California.
- Vejle hospital in Denmark.
- Dr. Damstra of Jij Smellinghe hospital Drachten, Netherlands.
- Dr. Granzow in Torrance, California.
- Dr. Mackie (trained by Dr. Munnoch) of Macquarie University, Sydney, Australia.
- Dr. Munnoch of Ninewells Hospital Dundee, Scotland.
- Other groups who advertise liposuction for lymphedema:
- Johns Hopkins Medicine in Baltimore, Maryland.
- Dr. Becker in Paris, France.
- Dr. Campisi in Genova, Italy. This well-known lymphatic microsurgical team also performs their own version of liposuction that includes the use of dyes to help visualize and thus avoid damage to lymphatic vessels (termed “Fibro-Lipo-Lymph-Aspiration with a Lymph Vessel Sparing Procedure [FLLA-LVSP]”. They recently published clinical data demonstrating the results of their approach (ref 8).
- Dr. Dancey in Birmingham, England.
- Dr. Taylor (Head and Neck Lymphedema), Division of Otolaryngology Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.
We cannot recommend any particular surgeon or team, nor can we vouch for their qualifications or capabilities. This list is included for information purposes only. If you know of additional specialists who claim to offer liposuction for lymphedema, please comment below and I will include them in this list.
As with other surgical procedures, liposuction for lymphedema involves risks, is invasive, and expensive. One article I read quoted prices starting from $8,000 AUD for the procedure at Macquarie University in Australia.
If delivered by a trained surgical team in conjunction with ongoing lymphedema management best practices (including wearing compression garments), specialized liposuction for lymphedema can effectively and significantly reduce limb volume in patients with stage 3 primary or secondary lymphedema that is otherwise unresponsive to conservative treatment.
Far from being only a ‘cosmetic’ procedure, for some patients liposuction can significantly reduce functional disability and infection (and related hospitalization), while improving limb aesthetics and associated patient self-image. These positive health benefits warrant economic consideration by health insurance providers considering funding this procedure.
If you have experience with liposuction for lymphedema, or know of another team that offers this specialized service, please share in the comments section below :)
If you are interested in surgical options for less advanced cases of lymphedema, please check out our article on lymphatic venous anastomosis (LVA).
- Brorson H, Ohlin K, Olsson G, Karlsson MK. Breast cancer-related chronic arm lymphedema is associated with excess adipose and muscle tissue. Lymphat Res Biol. 2009; 7(1):3–10. https://doi.org/10.1089/lrb.2008.1022
- Brorson H, Svensson H. Liposuction combined with controlled compression therapy reduces arm lymphedema more effectively than controlled compression therapy alone. Plast Reconstr Surg. 1998; 102(4):1058–1067. abstract
- Brorson H, Svensson H, Norrgren K, Thorsson O. Liposuction reduces arm lymphedema without significantly altering the already impaired lymph transport. Lymphology. 1998; 31(4):156–172. abstract
- Brorson H. Liposuction in Lymphedema Treatment. J Reconstr Microsurg. 2016 Jan; 32(1):56-65. abstract
- Schaverien MV, Munro KJ, Baker PA, Munnoch DA. Liposuction for chronic lymphoedema of the upper limb: 5 years of experience. J Plast Reconstr Aesthet Surg. 2012; 65(7):935–942. https://doi.org/10.1016/j.bjps.2012.01.021
- Lee D, Piller N, Hoffner M, Manjer J, Brorson H. Liposuction of postmastectomy arm lymphedema decreases the incidence of erysipelas. Lymphology 2016; 49:85-92. abstract
- Granzow JW, Soderberg JM, Kaji AH, Dauphine C. Review of Current Surgical Treatments for Lymphedema. Ann Surg Oncol. 2014 Apr; 21(4):1195-201. https://doi.org/10.1245/s10434-014-3518-8
- Campisi CC, Ryan M, Boccardo F, Campisi C. Fibro-Lipo-Lymph-Aspiration With a Lymph Vessel Sparing Procedure to Treat Advanced Lymphedema After Multiple Lymphatic-Venous Anastomoses: The Complete Treatment Protocol. Ann Plast Surg. 2017 Feb;78(2):184-190. abstract
Surprised of the conspicuous absence of Prof/Dr CA Campisi, aided by Dr CC Campisi (Genoa, in the “cradle of lymphology” Italy)
Happy to provide more information – as someone who researched LE care for many years before exhausting “intensive conservative therapeutic treatment” @ Wittlingertherapiezentrum in Wachsee, Austria, & then research surgical/microsurgical options for my extreme LE (2010-2012), the Campisi approach stood out as THE option. Firsthand consultations conducted at ILF2011, Toronto, bore this out. Forty years of successful experience & expertise was exactly what my case needed.
Great, thorough & thoughtful article, which I will share on the LE-dedicated FB page: “Lymphedema – LE Nexus Canada”
Good health & best regards,
Stephen (Steve) Kelland
P.S. – as LE&RN: Canada Chapter, Chair, I am somewhat disappointed that your piece was not released during March (“Lymphedema Month”), especially “World Lymphedema Day – 6 March”! I invite you & welcome a visit to my FB page. Cheers!
Thanks so much Steve for your blisteringly fast and thoughtful response! I’m happy for you and impressed that you successfully navigated yourself to the right expert hands, and a good outcome :) We will certainly check out your facebook page. Lindsay and I are aware of Dr Campisi, although not personally. His team was originally overlooked when we put this article together because we weren’t clear that they performed liposuction regularly and independently of their microsurgical approaches- but in hindsight, even if they tend to only use lyposuction on their microsurgical patients, it’s still worth including them here. So I have added them above. Thanks again! Ryan
P.S. – we were actually trying to publish this article in March, but Lindsay was also busy preparing a new talk (among numerous other things) and so she couldn’t fit it in :)
Dr. Davey – thanks for this follow-up, including the added reference plus the info re: the ‘near miss’ of this helpful piece being published during THE month for the Lymphedema Community which, since establishment of “World Lymphedema Day” (6 March 2016), no longer recognizes national boundaries in its fight vs. Lymphedema (LE).
While the earlier submitted comment was specific to this appreciated article, this comment offers a more general ‘thank you’ to Toronto Physiotherapy for continuing published research & insights into LE.
Please keep up the good (& informative!) work.
Canada MALE (Male Advicate for LymphEdema) |
FB: Lymphedema – LE Nexus Canada ✌️
Hello, Can you advise if Dr. Michel Alain Danimo and Dr. Ali Izadpanah have acquired training for lymphedema liposuction? They are two Plastic Surgeons, part of a Team, at the Centre hospitalier de l’Universite de Montreal; and who are now offering are now offering patients LVA surgery. The first lymphovenous bypass surgery was in January 22, 2018. Both doctors have had training in microsurgery (Dr. Danino in Japan and Dr. Izadpanah in the US). It would interesting to know if also have specific training for liposuction in lymphedema patients. Thank you.
Hello Connie. I’m thrilled to hear that more centers in Canada may now be starting to invest in the training of their vascular and/or plastic surgeons in this specific niche, where there is certainly a need. I am not sure whether Dr. Danino or Dr. Izadpanah have additional training in the lymphedema-liposuction, you would likely need to reach out to their offices directly to inquire if they are accepting referrals for this particular diagnosis (perhaps they could at least consult?). Wishing you the best of luck Connie, in this burgeoning field! Sincerely, Lindsay Davey
What can be done for stage 4 lymphedema? Is there liposuction surgery available for me?
Dr. Wei Chen of the Cleveland Clinic Foundation offers this procedure in Cleveland, Ohio.
Is there a doctor in New Jersey that specializes in this procedure??
Can anyone tell me if there is anyone in Calgary; Alberta trained to do this surgery
Dr. Kennedy in Calgary, Alberta. I am scheduled for Liposuction, ulnar nerve repair and bypass surgery in July 2021. I was 32 years old when I got cellulitis on my left arm which caused lymphedema. It’s been 14 years and I have had over a dozen cellulitis episodes.
I have just had this procedure and am just a few months out of surgery.
After having read your article I think there are a few things that you have not mentioned that are significant and important to have included
1. The recovery is rough. In fact it’s the toughest thing I’ve ever been through, And I have been through a lot with my lymphedema.. It’s a violent procedure internally and the post surgical swelling is significant and relatively long lasting. Even though I had 12 pounds removed from my leg through this procedure, and my leg looks excellent- At this moment I am 30 pounds heavier than I was the day of surgery. All swelling in the rest of my body from the inflammation caused by the surgery. It is expected to go down over the next six months. And I’m probably eating 8 ounces of food per today over the last 8 weeks.
Each of the patients I have spoken to has had a significant weight gain (25-30 lbs) following surgery and it is long lasting and it is very uncomfortable.
The next thing that people need to really truly understand and weigh- Is the compliance factor through discomfort. It as I said is a rough surgery to recovery from it is not an easy surgery to recover from. My limb is expected to require 1 year to heal.
The level of compression is different than anything I have been through in the many years I have used compression with 100% compliance. It is thick and it is multi layered flat knit – not circular – which is comfortable and thin – this is more akin to wearing a tight wetsuit 24/7 and I feel like I am being squeezed like a snake is choking me and I mean that and I cannot express to you enough, that is compression therapy, needs to be followed to 24 seven for the rest of your life. The double thick layers of ElvaRex is beyond tight. It’s extreme. And I kind of wish that I had the ability to walk around in this level of tightness for a few days before I considered this procedure because it is not insignificant. The success of the procedure requires significant compliance in wearing 24/7 of this heavy duty compression so this cannot be stressed enough that it’s really important to be able to handle it. To be able to handle discomfort and to be able to tolerate the level of compression that is going to be required for the rest of your life.
That’s said the results are significant immediately and that’s a very exciting thing to see. My reduction is good, my leg is indistinguishable from my unaffected leg in clothes and that’s very exciting.
So for the right person this surgery is a remarkable opportunity. But it needs to be considered very carefully with negatives as well because these are requirements they are not optional and consistency is key and you don’t get a choice.
This is such a helpful and detailed comment, I truly appreciate it. This personal experience with liposuction of your leg(s) is going to be very informative for many women considering this procedure, and actually, is very timely as there has just been published a new consensus document (by an international expert panel) regarding lipoedema, lipohypertrophy, lipo-lymphoedema, and related topics, and includes a section on liposuction and the evidence for candidacy for this procedure. We plan to summarize these findings in a blog post shortly. Stay tuned for that!
Compression is indeed prescribed post-surgery after liposuction and is indicated to help with post-operative swelling, optimal healing, and pain management. Having said that, if the higher level of compression than you’re used to (the flat knit style) is exceedingly uncomfortable and is limiting your mobility, I would discuss this with your plastic surgery/lymphedema team members, as there may be a better solution for you than this Elvarex style compression worn 24/7. Naturally, each case is different and thus each post-operative prescribed compression parameters can vary between surgeons and between patients, but to be sure, high compliance with wearing compression post-operatively is essential for optimal results, and it’s commendable that you are getting through it even with the level of challenge it presents.
Thank you again for your comments Janet. Wishing you all the best with your ongoing recovery,
I have had this procedure performed twice by Dr Kennedy in Calgary; once targeting the upper leg and the second primarily targeting the lower leg. Perhaps I’m an exception but my recovery was a breeze. I had no pain, in fact did not even take one pain killer. I was walking immediately and have had no weight gain post surgery. I have always been compliant with wearing compression 24-7. I found the many appointments for compression wrapping after surgery a bit inconvenient perhaps but I would highly recommend this procedure to anyone that is determined to be a good candidate!
The results have allowed me to feel better about myself and finally be able to purchase standard sizes of slacks without having one leg altered.
Hello Florida citizen here who developed Lymphedema five years ago and was willing to travel to Maryland to get treatment for it. However on the eve of doing a cash out refinance to afford the cost to do so I was recommended to DOCTOR KYLE XU from the University of Miami, He began aggressive LE massage therapy and other treatments. On September 15, 2021 he did lymph node transplant on my affected left leg where he transplanted lymph nodes from other areas of my body into my left leg artery and veins. One year later my leg has returned to its beautiful color and works like a charm. I am now scheduled for lymphedema Liposuction. DOCTOR KYLE XU is affiliated with The University of Miami located in Miami Florida and is possible the only surgeon I know in our neck of the woods. I beg you to add him to the lists of doctors as i am sure there are a few people who need his services locally.